No, not possible.
To meet the transport constraints, the heat load of each canister at HI-STORE will be less than 60% of the NRC-certified value for on-site storage. Thus, the heat generation rate in any canister stored at HI STORE CISF will be well below the thermal capacity of the storage system when it is first installed and then continuously decline from that point in accordance with the natural law of radioactive decay. The reduced heat load at the HI-STORE CISF ensures that a canister’s failure causing radiological release is not possible even if a saboteur were to miraculously evade the security forces and intrusion sensors, and have possession of the specially-engineered hardware that would be needed to block the air flow.
